What is CELEBREX?
CELEBREX (pronounced sell'-uh-brex) is for relief of the pain and inflammation of OA and adult RA and was introduced in the United States in early 1999. Since then, millions of CELEBREX prescriptions have been written, making it the #1 selling brand of prescription arthritis medication. By effectively reducing the pain, inflammation and stiffness of arthritis, CELEBREX can help you through the day with activities like standing, walking or climbing stairs, and through the night while sitting or lying in bed.
Who should I talk to if I have questions about CELEBREX?
We know that reading this factual booklet can never take the place of talks between you and your doctor or other healthcare professional (nurse, nurse practitioner, physician assistant, or pharmacist). Please be sure to talk to your doctor or other healthcare professional about any questions you have about CELEBREX. Only your doctor can assess the benefits and risks to decide if CELEBREX is right for you.
What is osteoarthritis?
Osteoarthritis (OA) is a condition that can result from wear and tear on the joints, like the knees, hips and fingers, or from an injury. Many people may have only mild discomfort. But as cartilage covering the ends of bones in the joints wears away, many people may have considerable pain, inflammation and loss of movement. OA affects all parts of a joint, causing pain and stiffness, especially after physical activity.
OA occurs more often as people grow older, and is the most common joint disease. About one third of people over age 35 show some signs of OA when they have x-rays.
In people over age 55, OA of the hip is more common in men and OA of the fingers is more common in women. OA of the knees causes problems for both. In the US, about 100,000 people can't walk from their beds to their bathrooms without help because of OA of the knee or hip.
In addition to aging, other risk factors for OA include being overweight, injuries and diabetes.
What is rheumatoid arthritis?
The main symptom of rheumatoid arthritis (RA) is inflammation — redness, heat and pain — at the joints. RA affects the joint membranes, cartilage and bones the way OA does. But unlike OA, RA can also affect the whole body — with loss of appetite, a general feeling of being unwell and other symptoms. No one knows exactly what causes RA, but it may be caused by the immune system (the body's defenses) turning against the body.
RA takes very different forms in different people. Some people have only a mild form of RA that does not get more severe. Others go on to develop severe deformities of the joints. Most people with RA fall somewhere in between.
RA is usually first noticed in the small joints of the hands, feet and wrists. It may then move on to the larger joints — elbows, shoulders and knees. As RA gets worse, the joints can become deformed and too stiff to move.
Rest is often very helpful when there is a flare up of RA, but too much rest can do more harm than good — especially in older people.
Some people have more stiffness after resting than after activity. Physical therapy and exercise directed by a healthcare professional can help a person with RA keep the ability to move for as long as possible.
RA affects about 1 in every 100 people. It affects women 3 times more often than men. The people most likely to develop RA are those between the ages of 35 and 50.
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